Down's syndrome, dementia, and superoxide dismutase

Superoxide dismutase Superoxide dismutase

Superoxide dismutase mimetics.

In this review we describe the potential role(s) of superoxide in inflammatory disorders.

Extracellular Superoxide Dismutase

Extracellular-superoxide dismutase is a tetrameric copper-containing glycoprotein that previously has been demonstrated to be the major superoxide dismutase of human extracellular fluids. The occurrence of this enzyme in various human tissues that were removed from two accidental death victims and in 19 different human cultured cell lines was determined. All investigated tissues were found to c...

Superoxide dismutase: master and commander?

I nhaled nitric oxide (NO) has long been known to be an effective pulmonary vasodilator in the normal pulmonary vasculature. In the classical NO signalling pathway, it activates soluble guanylate cyclase in the cytoplasm of pulmonary artery smooth muscle cells, leading to the production of cyclic guanosine monophosphate (cGMP), which then activates protein kinase G (PKG). PKG, acting through se...

Superoxide Dismutase and Sulfite Oxidation

DDTC, SOD, Sulfite Oxidation 50 U SOD in 1 ml or 10 m M DDTC do not much change sulfite oxidation due to the free radicals procuding system xanthin-xanthin oxidase. Sulfite oxidation due to the activity of this free radicals producing system proceeds probably as the univalent oxidation o f sulfite. The role o f SOD in SO, resistance mechanism in plants and the role o f DDTC as S 0 2 oxidation e...